Subject Description

THERMODYNAMIC MODELLING OF CHEMICAL PROCESSES

Advanced thermodynamics. Phase equilibrium: advanced methods of correlation, phase space, high pressure, electrolytes. EoS, alpha functions, mixing rules. Phases Resolution in multi-component systems. Chemical equilibrium: complex reaction systems. Minimization methods for Gibbs free energy. Processes design based on entropy minimization. Cooling systems and CHP, reactors integration.

 


ANALYSIS OF TRANSPORT PHENOMENA

Generalization of transport laws. General equation of conservation of any extensive property. Microscopic conservation equations. Application to systems with molecular and turbulent transport. Theories of the boundary layer.  Analogies between transport phenomena.

 


DYNAMIC SIMULATION OF CHEMICAL PROCESSES

Basic concepts and types of systems. Fields of application. Numerical methods. Simulation languages. Dynamical systems and bifurcations. Simulation of distributed parameter systems, PDE. Discontinuities and variable structure systems. Models calibration. Model validation. Reduced models. Application in biological systems and processes. Methodology for simulation projects with applications to analysis, control and process optimization.

 


OPTIMIZATION OF CHEMICAL PROCESSES

Basics. Methodology and problem formulation. Unconstrained optimization. Algorithms for constrained optimization LP, NLP. Mixed-integer Methods, MINLP. Software optimization, GAMS. Applications: Process design with optimization. Operating points optimization. Modeling superstructures. Exchanger network synthesis. Batch processes, planning and sequencing.

 


SAFETY, HEALTH AND ENVIRONMENT

INTRODUCTION: Industrial activity and environment; Environmental policy; Environmental legislation; Sustainable development. THE ENVIRONMENTAL IMPACT OF INDUSTRY: Water pollution, air pollution, solid and hazardous waste; Resource consumption; Pollution treatment systems. POLLUTION PREVENTION: Waste minimization; Best available techniques; Water conservation; Fugitive emissions. LIFE-CYCLE ASSESSMENT: Methodology for analyzing life-cycle; Inventory analysis; Resolution of practical cases. ANALYSIS OF ENVIRONMENTAL RISKS: Legal framework; Analysis and evaluation of environmental risks; Risk Analysis Methodology; Decision analysis; Environmental emergency plan; Integration of safety, environmental health and environment. ENVIRONMENTALLY FRIENDLY DESIGN: Cleaner Production; Eco-efficiency; Green chemistry; Ecodesign; Ecoproducts.

 


CHEMICAL PRODUCT ENGINEERING

INTRODUCTION TO INNOVATION IN PRODUCT:  1. Scientific and technological surveillance applied to product development. IP protection: patents, trademarks and trade names. 2. Sustainability in the product. Lifecycle. Carbon footprint and water footprint. The responsibilities of the chemical process industry. 3. Types of products. Raw materials. Devices to perform a function. Products for a specific application. Microstructures. Nanotechnology.
PRODUCT DEVELOPMENT: 4. Formulation of active compounds in liquid phase: emulsions, nano-suspensions, micelles and liposomes. 5. Formulation of active compounds in solid phase I. Micro / nanoparticles. Methods “Top-down”: milling and ultra-homogenization. Business methods. Methods “Bottom-up”: crystallization / precipitation. 6. Formulation of active compounds in solid phase II. Encapsulation of active compounds. Encapsulation materials. Encapsulation techniques. Coacervation. Spray drying. Nano-encapsulation techniques. 7. New technologies applied to the formulation of active compounds. Supercritical fluids as solvents and cosolvents. Supercritical fluids as anti-solvents.
PRODUCT DEVELOPMENT: 8. Development of a system based on a natural extract for use as a functional food, cosmetic, pharmaceutical and / or plant protection product. 9. Experimental development of a product. Emulsion formulation. Evaporation of organic solvent, and spray drying. 10. Marketing of products. The Market. The sellers. Buyers. Product marketing proposal designed. 11. Opportunities in product innovation.

 


REACTION PROCESS ENGINEERING

Analysis of chemical reaction processes. Fundamental equations. Systems reaction and flow models. Complex reactions. Local and overall selectivity. Optimization of reactor configuration. Heterogeneous reactors. Fixed Bed Catalytic Reactor: simple and complex models. Fluidized Bed Catalytic Reactor. Three Phase Reactors: trickle.-bed reactor and slurry reactor. Calculation methods. Non-ideal flow. Macromixing approach. Simple and combined models. Micromixing.

 


MASS TRANSFER PROCESS DESIGN

Less frequent operations. Multicomponent separations. Kinetic controlled separations. Selection, analysis and design of separation processes and operations.

 


CHEMICAL PROCESS ANALYSIS WITH SIMULATORS

THERMODYNAMIC MODELING: Methods & Models; Thermo Data Engine; Reliable Definition of New Components. STEADY SIMULATION WITH HYSYS: Interface
Basic modeling; Modeling tools; Reporting. DYNAMIC SIMULATION WITH HYSYS: Moving from steady state to dynamics; Controllers; Event Scheduler, start-up and shut-down.

 


PRODUCTION MANAGEMENT

Introduction. Capacity. Location. Methods and time. Stock management. Added plan. Master Production Plan. MRP (Material Requirements Planning). Sequencing. JIT (Just In Time). TOC (Theory Of Constraints). Lean Manufacturing.

 


BUSSINESS MANAGEMENT

Introduction to Management. Functional areas.  Analysis and interpretation of financial statements. Cost accounting. Economic feasibility of projects. Human Resource Management.

 


SUSTAINABILITY AND EXCELLENCE

SUSTAINABILITY PRINCIPLES, FIELDS AND APPLICATIONS: 1. Definition of sustainability principles and inspiring disciplines. 2. Sustainability Metrics. EXCELLENCE AND MANAGEMENT: 3. Excellence in manufacturing and quality management. INNOVATION, CREATIVITY AND ENTREPRENEURSHIP: 4. Creativity and innovation. 5. Entrepreneurship in the process industry. SUSTAINABLE BUSINESS PROJECT (CASE STUDY).